Polynucleotide (PN) skin booster is an advanced form of regenerative therapy that harnesses the natural healing power of DNA fragments to rejuvenate the skin. Extracted from fish sources, these bio-compatible molecules stimulate cell repair, improve hydration, and restore youthful elasticity, making them a sought-after solution for anti-ageing, acne scars, and overall skin revitalisation.
What are polynucleotides?
Polynucleotides are DNA fragments known for their ability to stimulate skin repair and regeneration. When injected into the skin, these bio-compatible molecules activate fibroblasts (the skin cells responsible for producing collagen and elastin), reduce inflammation, and enhance hydration, resulting in firmer, healthier, and more radiant skin.
Key effects of PN skin booster
• Stimulating fibroblast activity, promoting the production of collagen and elastin.
• Enhancing cellular repair and regeneration.
• Improving skin texture, tone, and elasticity.
• Providing deep hydration, especially beneficial for aged or damaged skin.
We offer two types of PN skin booster, each sourced from different origins and tailored to specific skin needs:
Salmon PN from South Korea
Trout PN from Italy
While both share the core function of promoting skin regeneration, they differ slightly in composition and targeted benefits.
Viscosity variants for different treatment needs
Both salmon and trout PN boosters come in varying viscosities to suit different treatment needs:
For scar treatment, we offer PN in an injectable formula of thicker viscosity, specially formulated to target scars and enhance skin healing processes. The thicker texture lifts depressed scars, prevents them from collapsing, and initiates repair of scar tissue more effectively.
For the delicate eye area, we offer PN in an injectable formula of lower viscosity, specially formulated to treat dark circles, wrinkles and puffiness. It is less viscous and softer compared to regular injectable PN, therefore, more comfortable and a shortened downtime as it causes fewer bumps post-procedure.
| Feature | Salmon PN | Trout PN |
|---|---|---|
| Origin | South Korea | Italy |
| Key Ingredient | Polynucleotides derived from salmon DNA | Polynucleotides derived from trout DNA |
| Primary Function | Skin healing, anti-inflammation, regeneration | Skin regeneration, hydration, fibroblast stimulation |
| Main Benefits | Repairs damaged skin, improves texture and deep acne scars | Deep hydration, boosts collagen, improves elasticity |
| Best For | Overall intensive repair, particularly for inflamed, or acne-damaged skin | Aged skin, fine lines, dry skin, or overall comprehensive rejuvenation |
| Treatment Areas | Face, neck, under-eye | Face, neck, décolleté, hands |
| Anti-inflammatory Effect | Strong | Moderate |
| Hydration Boost | Moderate | High |
| Texture Refinement | Improves pores and acne scars | Enhances elasticity and skin density |
Common post-treatment complications include redness, swelling and bruising. You may begin to notice gradual improvement 3-4 weeks after the first treatment, full results are observed after four treatment sessions.
A typical treatment program is made up of four initial syringes, with a syringe administered once every three weeks. Thereafter, one syringe every six months is recommended for maintenance.
PN skin booster is usually combined with subcision, TCA Cross, MicroLaserPeel, and resurfacing erbium YAG laser as part of our scar revision treatment program.
The choice between salmon PN and trout PN depends on your skin condition, age, and desired results. We will determine the most suitable treatment protocol tailored to your goals.
If you’re looking to deeply repair and restore youthful structure to your skin, salmon PN may be ideal. For those aiming to combat signs of ageing and boost skin hydration with a more refined glow, trout PN could be the better fit.
This is an innovative skin rejuvenation treatment that combines the benefits of polynucleotides (PN) and hyaluronic acid (HA) in a single injectable solution. Derived from salmon or trout DNA, polynucleotides are known for their regenerative properties, they enhance skin’s renewal ability, improve elasticity, and exert an anti-inflammatory effect. While polynucleotides increase fibroblast, elastin, and collagen production, HA focuses on hydration due to its ability to retain many times its weight in water, think of it as a sponge, absorbing and holding water. As ageing occurs, the body’s ability to produce HA reduces, replenishment of HA creates luminous and dewy skin by drawing water back into cells.
This injectable treatment offers a unique combination of skin-boosting ingredients, providing immediate hydration from HA and regenerative effects from PN. It addresses multiple signs of ageing and skin concerns in a single treatment, and is ideal for anyone looking for a fuss-free experience with rapid results.
The treatment is safe and can be performed every month.
The treatment is a lot more comfortable than other injectables due to the addition of lidocaine, which reduces pain. In addition, numbing cream will be applied before treatment.
Collagen, accounting for 30% of all proteins, maintains skin elasticity and firmness, and is responsible for the adhesion and regeneration of cells that make up the connective tissue. From the age of 25, we lose approximately 1% of collagen annually, this combined with the deterioration in the quality of collagen fibers result in loss of volume, crepey skin, wrinkles and fine lines, and an aged appearance.
The injection of HTIC stimulates the natural repair and regrowth of connective tissue by boosting the production of fibroblasts and Type III Collagen, leading to noticeable improvements in skin texture and firmness. The formula is well-tolerated, making it a safe option for all.
Softens fine lines and wrinkles
Improves skin laxity
Improves appearance of acne scars and pores
Improves appearance of stretch marks
Enhances overall skin quality
Side effects are minimal. You may notice small bumps and redness at the injection sites, bruising may also occur. Usual activities may be resumed immediately after treatment.
For optimal results, it is recommended to have one session every two weeks for a total of four sessions. After the initial set of four sessions, you can maintain your results with a session every four to six months.
The treatment is a lot more comfortable than other injectables
due to the addition of lidocaine, which reduces pain. In addition,
numbing cream will be applied before treatment.
Injectable HTIC can be combined with the following:
Botulinum toxin relaxes facial muscles to soften dynamic lines and restore a youthful appearance.
Botulinum toxin can improve the following conditions which include:
The onset of improvement usually starts within 3 days after treatment and the typical duration effect lasts around 3-6 months.
No! Botulinum toxin treatment gives a subtle, natural enhancement to one’s appearance. Futhermore, individuals can choose how subtle or dramatic they would like their results to be.
HIFU utilises fractional ultrasound energy to penetrate the skin to heat up the superficial and deeper skin layers, and the superficial muscular aponeurotic system (SMAS) layer. This process stimulates the formation of new collagen which leads to skin tightening, lifting, and facial firming. HIFU can be applied to the face, jawline and neck.
HIFU can improve the following conditions:
A typical treatment program is made up of four initial sessions, with a session done once every three months. Thereafter, one session every four to six months is recommended for maintenance.
HIFU is usually combined with BBL or injectable bio-remodelling HA for better rejuvenation results.
Local Dynamic Micro-Massage (LDM) treats skin problems in the epidermis and dermis. It utilises dual-frequency ultrasound technology at high frequencies to exert a strong micro-massage effect on tissue structures. The micro-massage activates fibroblasts, rejuvenates the skin matrix and connective tissue, enhances collagen cross-linking, and encourages healing at a cellular level. It treats a variety of dermatological issues and medical aesthetics concerns, improving overall skin health without any downtime.
1. Reduces “bad enzymes” Matrix Metalloproteinases (MMPS)
MMPs contribute to inflammation and collagen degradation, they also appear to be involved in connective tissue metabolic disorders resulting in conditions such as acne, eczema and dermatitis. Inhibiting MMPs returns the skin back to its normal collagen metabolic state.
2. Activates HSPs (heat shock proteins)
HSPs aid in skin immunity and strengthens its ability to heal. They are produced to help the skin combat stressful conditions such as exposure to extreme temperatures and UV radiation.
3. Increase GAGs (glycosaminoglycans)
GAGs accelerate cell metabolism and hyaluronan content in skin. By increasing tissue turgor, it improves texture, tone and strengthens the skin barrier.
Skin Ageing and Laxity
Fine lines, wrinkles, prominent nasolabial folds and marionette lines, skin rejuvenation and firming, body firming and toning.
Treatment of Chronic Skin Conditions
Dryness, acne, rosacea, flushing.
Scar Regeneration & Wound Healing
Hypertrophic scars, stretch marks, bruises.
Most ultrasound systems use a single frequency, typically in the range of 1 to a maximum of 5 MHz, the therapeutic effect is thus far below the superficial skin layers. LDM uses a special frequency of 10 MHz other than 1 and 3MHz, which allows the energy to work effectively on the epidermis and dermis, where disease processes take place. In addition, the system switches and combines frequencies at timed intervals, ensuing better dynamic pressure distribution in the tissue over several skin layers.
After cleansing the skin, a layer of gel is applied onto the treatment area, an ultrasound probe is then gently rolled over the intended area. The treatment is comfortable without any pain and downtime.
The treatment ranges from 15 to 30 minutes, depending on the indication or condition.
While improvement may be observed after just one session, for optimal and full results, LDM should be performed once every week or fortnight for the first six weeks. Maintenance sessions are recommended once every month to two months.
Dermatological conditions such as eczema or psoriasis may need up to eight treatments and in more complex and severe cases, ten to sixteen sessions.
Although LDM is a great treatment on its own, results are augmented when combined with other medical facial services, energy-based devices or injectables. In fact, it helps shorten procedural downtime by reducing inflammation, and increasing cell regeneration and metabolism.
Yes, LDM is suitable and safe for all skin types and colour.
Microneedling Radiofrequency treats melasma, diffuse redness, rosacea, and post-inflammatory hyperpigmentation. It is also effective in reducing fine lines and big pores, brightening skin tone, and rejuvenating the skin in general.
How Microneedling Radiofrequency works
Developed in Silicon Valley, the device delivers a therapeutic electromagnetic field of energy through an array of micro-insulated needles that penetrate the dermis at adjustable depths. The microneedling process invigorates the body’s natural healing cascade, triggering collagen and elastin generation, while the pulsed radiofrequency energy selectively targets the basement membrane zone, where abnormal vessels and pigment-producing cells are often concentrated.
Furthermore, the innovative SR3 (Selective Regional Regeneration Radio Repeated Pulse) technology enables the device to target abnormal blood vessels and pigmentation selectively without harming the surrounding healthy tissue, thereby, promoting melanin (pigment) regulation, vascular normalisation, and collagen remodelling.
Many individuals have a compromised basement membrance due to sun exposure and intrinsic ageing. Remodelling this very layer between the epidermis and dermis prevents the migration of pigment cells to the deeper dermal layer. The treatment targets the root causes of melasma by regulating hyperactive melanocytes (pigment cells), strengthening damaged basement membrane, removing abnormal blood vessels in the skin, and increasing collagen and young fibroblast production.
You may observe some lightening and a smoother skin texture after the first session. Full results are usually observed after 5 sessions, the treatment sessions are performed once every 3 weeks.
The treatment is virtually painless with numbing cream.
Immediately following the treatment, there may be some mild redness and swelling which typically resolves within an hour.
Most patients are able to resume activities immediately post-treatment.
SkinTyte utilises infrared technology to deeply heat dermal collagen. This process promotes partial denaturation and contraction of collagen. The heat also initiates the body’s natural healing process, which creates a renewed collagen foundation leading to increased skin firmness. Powerful sapphire cooling protects the entire treated surface during treatment, ensuring comfort and safety. SkinTyte can be applied to both the face and body including the abdomen, thighs, arms, buttocks, and lower back.
SkinTyte can improve the following conditions:
At least 5 sessions, with a session done once every 3 weeks. For maintenance, every 2 months.
SkinTyte is usually combined with BBL to boost overall rejuvenation.
V Form delivers a safe and effective treatment for body and facial contouring, cellulite reduction, and tightening of sagging skin following weight loss or pregnancy. V Form utilises CORE™ technology, a combination of multipolar radiofrequency energy and vacuum therapy. The vacuum suction increases blood microcirculation and lymphatic drainage while facilitating deeper penetration of the radiofrequency energy. The radiofrequency energy in turn, shrinks fat cells and heats the underlying network of collagen and elastin fibers, thereby, increasing skin elasticity. V Form can be applied to both the face and body including the abdomen, thighs, buttocks, lower back, arms and inner thighs.
V Form body can be combined with cryolipolysis. V Form face can be combined with PCR light or laser toning to boost overall rejuvenation.