Rejuran® HB plus is an innovative skin rejuvenation treatment that combines the benefits of polynucleotides (PNs) and hyaluronic acid (HA) in a single injectable solution. Derived from salmon DNA, PNs are known for their regenerative properties, they enhance skin’s renewal ability, improve elasticity, and exert an anti-inflammatory effect. While PNs increase fibroblast, elastin and collagen production, HA focuses on hydration due to its ability to retain many times its weight in water, think of it as a sponge, absorbing and holding water. As ageing occurs, the body’s ability to produce HA reduces, replenishment of HA creates luminous and dewy skin by drawing water back into cells.
This injectable treatment offers a unique combination of skin-boosting ingredients, providing immediate hydration from HA and regenerative effects from PNs. It addresses multiple signs of ageing and skin concerns in a single treatment, and is ideal for anyone looking for a fuss-free experience with rapid results.
The treatment is safe and can be performed every month.
The treatment is a lot more comfortable than other injectables due to the addition of lidocaine, which reduces pain. In addition, numbing cream will be applied before treatment.
1. Reduces “bad enzymes” Matrix Metalloproteinases (MMPS)
MMPs contribute to inflammation and collagen degradation, they also appear to be involved in connective tissue metabolic disorders resulting in conditions such as acne, eczema and dermatitis. Inhibiting MMPs returns the skin back to its normal collagen metabolic state.
2. Activates HSPs (heat shock proteins)
HSPs aid in skin immunity and strengthens its ability to heal. They are produced to help the skin combat stressful conditions such as exposure to extreme temperatures and UV radiation.
3. Increase GAGs (glycosaminoglycans)
GAGs accelerate cell metabolism and hyaluronan content in skin. By increasing tissue turgor, it improves texture, tone and strengthens the skin barrier.
Most ultrasound systems use a single frequency, typically in the range of 1 to a maximum of 5 MHz, the therapeutic effect is thus far below the superficial skin layers. LDM uses a special frequency of 10 MHz other than 1 and 3MHz, which allows the energy to work effectively on the epidermis and dermis, where disease processes take place. In addition, the system switches and combines frequencies at timed intervals, ensuing better dynamic pressure distribution in the tissue over several skin layers.
While improvement may be observed after just one session, for optimal and full results, LDM should be performed once every week or fortnight for the first six weeks. Maintenance sessions are recommended once every month to two months.
Dermatological conditions such as eczema or psoriasis may need up to eight treatments and in more complex and severe cases, ten to sixteen sessions.
Exosomes are tiny vesicles or “bubbles” released by various cells in the human body. They contain bioactive molecules such as growth factors, amino acids, lipids, peptides and genetic material. These nanoparticles act as messengers and transmit signals to unhealthy cells, triggering them to regenerate. As ageing occurs, our skin cells shrink and exosomes deplete, exosome treatment allows fresh exosomes to swoop in to instruct skin cells to repair and regenerate. Depending on the signal transmitted, this results in an exponential increase in collagen and elastin, reduced pigment production, improved wound healing, and reduced inflammation. Skin becomes visibly plumper, firmer, brighter and smoother.
The exosomes we use at s.k.MED are extracted meticulously from botanical stem cells and processed using patented technology. The end product is highly purified, contains 6 billion particles, 71 types of growth factors, more than 1000 regenerative proteins, and together with premier activators, ensures a holistic experience in skin rejuvenation.
The following six images depict the penetration of exosome nano particles into the skin over 24 hours.
Anti-inflammation
Potent antioxidant
Regeneration
Melanin modulation
The exosome treatment is performed alongside microneedling or laser therapy. These procedures create micro-channels in the skin which facilitate the penetration and absorption of the exosomes. In addition, exosomes work synergistically with the skin’s natural healing processes to maximise the benefits of the device-based treatments.
Exosome treatment addresses the following:
The treatment is virtually painless with numbing cream.
Microneedling Radiofrequency treats melasma, diffuse redness, rosacea and post-inflammatory hyperpigmentation. It is also effective in reducing fine lines, big pores, acne scars, brightening skin tone, and rejuvenating the skin in general.
Developed in Silicon Valley, Sylfirm uses multiple tiny electrodes to transmit a therapeutic electromagnetic field of energy that safely penetrates the dermal layer. The microneedling process triggers skin regeneration and collagen production, while the addition of radiofrequency energy further stimulates collagen production and skin’s natural healing response. Furthermore, the innovative SR3 (Selective Regional Regeneration Radio Repeated Pulse) technology reacts only to abnormal blood vessels and basement membrane, which normalises VEGF production (a protein that stimulates production of blood vessels) and remodels tissue membrane for dermal rejuvenation.
Many individuals have a compromised basement membrance due to sun exposure and intrinsic ageing. Remodelling this very layer between the epidermis and dermis prevents the migration of pigment cells to the deeper dermal layer. Sylfirm targets the root causes of melasma by regulating hyperactive melanocytes (pigment cells), strengthening damaged basement membrane, removing abnormal blood vessels in the skin, and increasing collagen and young fibroblast production.
You may observe some lightening and a smoother skin texture after the first session. Full results are usually observed after 5 sessions, the treatment sessions are performed once every 3 weeks.
The treatment is virtually painless with numbing cream.
Lutronic® Spectra™ Q-switched Nd YAG laser platform employs powerful efficacious wavelengths for superior results. With the addition of extended treatments, namely Gold Toning, RuVY Touch and Revital Treatment, the advanced laser system has the versatility to treat a variety of dermatological conditions with minimal downtime.
Sciton® long-pulsed Nd YAG laser selectively targets microstructures such as melanin, vessels and hair follicles. It is safe for all skin types, including tanned skin.
The treatment addresses multiple conditions which include:
For photorevelation, at least 5 sessions, with a session done once every 3 weeks. For maintenance, every 2 months. For hair removal and vascular treatments, the number of sessions will vary, your treatment plan will be personalised.
Photorevelation is usually combined with BBL to boost overall rejuvenation.
Rejuran® is one of the latest anti-ageing treatments that has surged in popularity across Asia. It delivers lasting results and offers a holistic approach to skin rejuvenation, addressing multiple signs of ageing and skin concerns in a single treatment. Manufactured in South Korea, Rejuran® contains polynucleotides that are derived from salmon DNA, which are known for their regenerative properties. The treatment boosts skin’s renewal ability, improves elasticity, and has an anti-inflammatory effect.
For scar treatment, we offer Rejuran® s, which is specially formulated to target scars and enhance skin healing processes. The thicker viscosity lifts depressed scars, prevents them from collapsing, and initiates repair of scar tissue more effectively.
For the delicate eye area, we offer Rejuran® i, which is specially formulated to treat dark circles, wrinkles and puffiness. It is less viscous and softer compared to regular Rejuran®, therefore, more comfortable and a shortened downtime as it causes fewer bumps post-procedure.
Common post-treatment complications include redness, swelling and bruising. You may begin to notice gradual improvement 3-4 weeks after the first treatment, full results are observed after four treatment sessions.
A typical treatment program is made up of four initial syringes, with a syringe administered once every three weeks. Thereafter, one syringe every six months is recommended for maintenance.
Injectable polynucleotides is usually combined with subcision, TCA Cross, MicroLaserPeel and resurfacing erbium YAG laser as part of our scar revision treatment program.
Profhilo® belongs to a class of bio-remodelling “injectable skincare” that addresses skin laxity and signs of ageing. This is achieved through the bio-stimulation of collagen, elastin and adipocyte stem cells that were lost through skin ageing. The treatment firms and tightens skin, boosts hydration, and improves skin texture.
Profhilo® offers one of the highest concentrations of hyaluronic acid (64mg/2ml) among the different types of injectables. This is made possible with NAHYCO® Technology, where 32mg of high molecular HA and 32mg of low molecular HA bind together through thermal cross-linking to form the Hybrid Cooperative Complex Hyaluronic (HCC) Acid. This reduces post-procedural inflammatory response and allows higher spreadability, which in turn translates to a better safety profile, fewer injection points, and reduced downtime.
Administration of a full 2 ml syringe requires only 5 injection points on each side of the face or neck. This reduces discomfort and the risk of bruising or haematoma.
Side effects are minimal. You may notice small bumps at the injection sites, bruising may also occur. The benefits will not be immediately visible, full results are typically observed 4-8 weeks after the second syringe.
A typical treatment program is made up of two syringes, administered 4 weeks apart, a third syringe may be necessary for patients with more severe laxity. Maintenance sessions should be repeated every 6-9 months.
Injectable biostimulators can be combined with HIFU or SkinTyte for maximal skin tightening and lifting.