Polynucleotide (PN) Skin Booster is an advanced regenerative therapy that harnesses the natural healing power of DNA fragments to rejuvenate the skin. Extracted from fish sources, these biocompatible molecules stimulate cellular repair, improve hydration, and restore youthful elasticity, making them a sought-after solution for anti-ageing, acne scarring, and overall skin revitalisation.
What Are Polynucleotides?
Polynucleotides are DNA fragments known for their remarkable ability to stimulate skin repair and regeneration. When injected into the skin, these biocompatible molecules activate fibroblasts (the cells responsible for producing collagen and elastin), reduce inflammation, and boost hydration. The result is firmer, healthier, and more radiant skin.
Key Effects of PN Skin Booster
We offer two types of PN skin boosters, each sourced from different origins and tailored to specific skin concerns:
While both types promote skin regeneration, they vary slightly in composition and targeted benefits, allowing for more individualised treatment outcomes.
Viscosity Variants for Different Treatment Needs
Both salmon and trout PN boosters are available in varying viscosities to suit specific treatment areas:
In summary, PN skin boosters offer a versatile and highly effective solution for skin repair, hydration, and rejuvenation—with tailored options for a wide range of skin concerns.
| Feature | Salmon PN | Trout PN |
|---|---|---|
| Origin | South Korea | Italy |
| Key Ingredient | Polynucleotides derived from salmon DNA | Polynucleotides derived from trout DNA |
| Primary Function | Skin healing, anti-inflammation, regeneration | Skin regeneration, hydration, fibroblast stimulation |
| Main Benefits | Repairs damaged skin, improves texture and deep acne scars | Deep hydration, boosts collagen, improves elasticity |
| Best For | Overall intensive repair, particularly for inflamed, or acne-damaged skin | Aged skin, fine lines, dry skin, or overall comprehensive rejuvenation |
| Treatment Areas | Face, neck, under-eye | Face, neck, décolleté, hands |
| Anti-inflammatory Effect | Strong | Moderate |
| Hydration Boost | Moderate | High |
| Texture Refinement | Improves pores and acne scars | Enhances elasticity and skin density |
Post-treatment side effects may include redness, swelling, and bruising. Gradual improvement can typically be seen 3–4 weeks after the initial treatment, with full results becoming apparent after four treatment sessions.
A typical treatment program is made up of four initial syringes, with a syringe administered once every three weeks. Thereafter, one syringe every four to six months is recommended for maintenance.
PN skin booster is usually combined with subcision, TCA Cross, MicroLaserPeel, and resurfacing erbium YAG laser as part of our scar revision treatment program.
The choice between salmon PN and trout PN depends on your skin condition, age, and desired results. We will determine the most suitable treatment protocol tailored to your goals.
If you’re looking to deeply repair and restore youthful structure to your skin, salmon PN may be ideal. For those aiming to combat signs of ageing and boost skin hydration with a more refined glow, trout PN could be the better fit.
This innovative skin rejuvenation treatment combines the benefits of polynucleotides (PN) and hyaluronic acid (HA) in a single injectable solution. Derived from salmon or trout DNA, polynucleotides are renowned for their regenerative properties—they enhance the skin’s natural renewal processes, improve elasticity, and provide anti-inflammatory effects. While PN boosts fibroblast activity and stimulates elastin and collagen production, HA focuses on hydration, thanks to its ability to retain many times its weight in water. Think of HA as a sponge, drawing in and holding moisture within the skin.
As we age, the body’s natural production of HA declines. Replenishing it helps restore hydration, resulting in luminous, dewy skin.
This injectable treatment offers a powerful synergy of skin-revitalising ingredients: immediate hydration from HA and long-term regenerative effects from PN. It addresses multiple signs of ageing and skin concerns in one treatment, making it ideal for those seeking a low-maintenance solution with fast, visible results.
Common post-treatment side effects include redness, swelling, and bruising, which resolve quickly. Results may be observed after the first treatment session as the combination of PN and HA delivers intense hydration and rapid regeneration.
The treatment is safe and can be performed every month.
The treatment is a lot more comfortable than other injectables due to the addition of lidocaine, which reduces pain. In addition, numbing cream will be applied before treatment.
Yes, the treatment can be performed on all skin types.
This treatment belongs to a class of bio-remodelling “injectable skincare” that targets skin laxity and signs of ageing. By bio-stimulating the skin to produce and replace collagen, elastin, and adipocyte stem cells lost through the natural ageing process, it firms and tightens the skin, boosts hydration, and improves skin texture.
The injectable material boasts one of the highest concentrations of hyaluronic acid (64mg/2ml) among various types of injectables. This is made possible with NAHYCO® Technology, where 32mg of high molecular weight HA and 32mg of low molecular weight HA are bound together through thermal cross-linking to form the Hybrid Cooperative Complex (HCC) Hyaluronic Acid. The result is a stable, long-lasting product that spreads smoothly under the skin without the need for chemical cross-linking agents. This helps minimise post-procedural inflammation, enhances spreadability, and offers a superior safety profile with fewer injection points and reduced downtime.

Administration of a full 2 ml syringe requires only 5 injection points on each side of the face or neck. This reduces discomfort and the risk of bruising or haematoma.

Side effects are minimal. You may notice small bumps at the injection sites, bruising may also occur. The benefits will not be immediately visible, full results are typically observed 4-8 weeks after the second syringe.
A typical treatment program is made up of two syringes, administered 4 weeks apart, a third syringe may be necessary for patients with more severe laxity. Maintenance sessions should be repeated every 6-9 months.
Bio-remodelling HA can be combined with HIFU or SkinTyte for maximal skin tightening and lifting.
Botulinum Toxin is a quick, effective treatment to soften dynamic wrinkles caused by repetitive facial movements such as frowning, squinting, or smiling. By temporarily relaxing targeted muscles, it smooths fine lines on the forehead, between the brows, and around the eyes, while preserving natural facial expressions. It is also used for jawline slimming by reducing the size of the masseter muscles, creating a more contoured, V-shaped facial profile. Results typically appear within a few days and last up to 3–4 months. With minimal discomfort and no downtime, it’s an ideal option for those seeking a refreshed, more youthful appearance.
Botulinum toxin can improve the following conditions which include:
The onset of improvement usually starts within 3 days after treatment, and the typical duration effect lasts around 3-6 months.
No! Botulinum toxin treatment gives a subtle, natural enhancement to one’s appearance. Futhermore, individuals can choose how subtle or dramatic they would like their results to be.
Collagen, which accounts for 30% of all proteins, plays a crucial role in maintaining skin elasticity and firmness. It is also responsible for the adhesion and regeneration of cells that form the connective tissue. From the age of 25, we lose approximately 1% of collagen annually. This, combined with the deterioration in the quality of collagen fibres, leads to a loss of volume, crepey skin, wrinkles, fine lines, and an overall aged appearance.
The injection of HTIC stimulates the natural repair and regeneration of connective tissue by boosting the production of fibroblasts and Type III collagen. This results in noticeable improvements in skin texture and firmness. The formula is well-tolerated, making it a safe option for all skin types.
Side effects are minimal. You may notice small bumps and redness at the injection sites, bruising may also occur. Usual activities may be resumed immediately after treatment.
For optimal results, it is recommended to have one session every two weeks for a total of four sessions. After the initial set of four sessions, you can maintain your results with a session every four to six months.
The treatment is a lot more comfortable than other injectables
due to the addition of lidocaine, which reduces pain. In addition,
numbing cream will be applied before treatment.
Injectable HTIC can be combined with the following:
As ageing occurs, the body’s ability to produce hyaluronic acid is reduced. Combined with external elements, the skin becomes dry, rough and less elastic. Through micro-injections of hyaluronic acid, skin booster treatment creates luminous and dewy skin by improving the skin’s ability to retain moisture.
Skin booster can improve the following conditions:
Skin booster is safe. Common post-treatment complications include redness, bruising and swelling. The application of aftercare products will ease the symptoms.
A typical treatment program is made up of three initial syringes, with a syringe administered once every 4 weeks. Thereafter, one syringe every 4-6 months for maintenance is recommended.