Botulinum Toxin is a quick, effective treatment to soften dynamic wrinkles caused by repetitive facial movements such as frowning, squinting, or smiling. By temporarily relaxing targeted muscles, it smooths fine lines on the forehead, between the brows, and around the eyes, while preserving natural facial expressions. It is also used for jawline slimming by reducing the size of the masseter muscles, creating a more contoured, V-shaped facial profile. Results typically appear within a few days and last up to 3–4 months. With minimal discomfort and no downtime, it’s an ideal option for those seeking a refreshed, more youthful appearance.
Botulinum toxin can improve the following conditions which include:
The onset of improvement usually starts within 3 days after treatment, and the typical duration effect lasts around 3-6 months.
No! Botulinum toxin treatment gives a subtle, natural enhancement to one’s appearance. Futhermore, individuals can choose how subtle or dramatic they would like their results to be.
Collagen, which accounts for 30% of all proteins, plays a crucial role in maintaining skin elasticity and firmness. It is also responsible for the adhesion and regeneration of cells that form the connective tissue. From the age of 25, we lose approximately 1% of collagen annually. This, combined with the deterioration in the quality of collagen fibres, leads to a loss of volume, crepey skin, wrinkles, fine lines, and an overall aged appearance.
The injection of HTIC stimulates the natural repair and regeneration of connective tissue by boosting the production of fibroblasts and Type III collagen. This results in noticeable improvements in skin texture and firmness. The formula is well-tolerated, making it a safe option for all skin types.
Side effects are minimal. You may notice small bumps and redness at the injection sites, bruising may also occur. Usual activities may be resumed immediately after treatment.
For optimal results, it is recommended to have one session every two weeks for a total of four sessions. After the initial set of four sessions, you can maintain your results with a session every four to six months.
The treatment is a lot more comfortable than other injectables
due to the addition of lidocaine, which reduces pain. In addition,
numbing cream will be applied before treatment.
Injectable HTIC can be combined with the following:
Polynucleotide (PN) Skin Booster is an advanced regenerative therapy that harnesses the natural healing power of DNA fragments to rejuvenate the skin. Extracted from fish sources, these biocompatible molecules stimulate cellular repair, improve hydration, and restore youthful elasticity, making them a sought-after solution for anti-ageing, acne scarring, and overall skin revitalisation.
What Are Polynucleotides?
Polynucleotides are DNA fragments known for their remarkable ability to stimulate skin repair and regeneration. When injected into the skin, these biocompatible molecules activate fibroblasts (the cells responsible for producing collagen and elastin), reduce inflammation, and boost hydration. The result is firmer, healthier, and more radiant skin.
Key Effects of PN Skin Booster
We offer two types of PN skin boosters, each sourced from different origins and tailored to specific skin concerns:
While both types promote skin regeneration, they vary slightly in composition and targeted benefits, allowing for more individualised treatment outcomes.
Viscosity Variants for Different Treatment Needs
Both salmon and trout PN boosters are available in varying viscosities to suit specific treatment areas:
In summary, PN skin boosters offer a versatile and highly effective solution for skin repair, hydration, and rejuvenation—with tailored options for a wide range of skin concerns.
| Feature | Salmon PN | Trout PN |
|---|---|---|
| Origin | South Korea | Italy |
| Key Ingredient | Polynucleotides derived from salmon DNA | Polynucleotides derived from trout DNA |
| Primary Function | Skin healing, anti-inflammation, regeneration | Skin regeneration, hydration, fibroblast stimulation |
| Main Benefits | Repairs damaged skin, improves texture and deep acne scars | Deep hydration, boosts collagen, improves elasticity |
| Best For | Overall intensive repair, particularly for inflamed, or acne-damaged skin | Aged skin, fine lines, dry skin, or overall comprehensive rejuvenation |
| Treatment Areas | Face, neck, under-eye | Face, neck, décolleté, hands |
| Anti-inflammatory Effect | Strong | Moderate |
| Hydration Boost | Moderate | High |
| Texture Refinement | Improves pores and acne scars | Enhances elasticity and skin density |
Post-treatment side effects may include redness, swelling, and bruising. Gradual improvement can typically be seen 3–4 weeks after the initial treatment, with full results becoming apparent after four treatment sessions.
A typical treatment program is made up of four initial syringes, with a syringe administered once every three weeks. Thereafter, one syringe every four to six months is recommended for maintenance.
PN skin booster is usually combined with subcision, TCA Cross, MicroLaserPeel, and resurfacing erbium YAG laser as part of our scar revision treatment program.
The choice between salmon PN and trout PN depends on your skin condition, age, and desired results. We will determine the most suitable treatment protocol tailored to your goals.
If you’re looking to deeply repair and restore youthful structure to your skin, salmon PN may be ideal. For those aiming to combat signs of ageing and boost skin hydration with a more refined glow, trout PN could be the better fit.
This innovative skin rejuvenation treatment combines the benefits of polynucleotides (PN) and hyaluronic acid (HA) in a single injectable solution. Derived from salmon or trout DNA, polynucleotides are renowned for their regenerative properties—they enhance the skin’s natural renewal processes, improve elasticity, and provide anti-inflammatory effects. While PN boosts fibroblast activity and stimulates elastin and collagen production, HA focuses on hydration, thanks to its ability to retain many times its weight in water. Think of HA as a sponge, drawing in and holding moisture within the skin.
As we age, the body’s natural production of HA declines. Replenishing it helps restore hydration, resulting in luminous, dewy skin.
This injectable treatment offers a powerful synergy of skin-revitalising ingredients: immediate hydration from HA and long-term regenerative effects from PN. It addresses multiple signs of ageing and skin concerns in one treatment, making it ideal for those seeking a low-maintenance solution with fast, visible results.
Common post-treatment side effects include redness, swelling, and bruising, which resolve quickly. Results may be observed after the first treatment session as the combination of PN and HA delivers intense hydration and rapid regeneration.
The treatment is safe and can be performed every month.
The treatment is a lot more comfortable than other injectables due to the addition of lidocaine, which reduces pain. In addition, numbing cream will be applied before treatment.
Yes, the treatment can be performed on all skin types.
Microneedling Radiofrequency is an advanced treatment for melasma, diffuse redness, rosacea, and post-inflammatory hyperpigmentation. It is also effective in reducing fine lines and enlarged pores, brightening the complexion, and rejuvenating the skin in general.
How Microneedling Radiofrequency Works
Developed in Silicon Valley, the device delivers a therapeutic electromagnetic field through an array of micro-insulated needles that penetrate the dermis at adjustable depths. This microneedling process stimulates the body’s natural healing cascade, triggering the production of collagen and elastin. Simultaneously, pulsed radiofrequency energy selectively targets the basement membrane zone, an area where abnormal blood vessels and pigment-producing cells are often concentrated.
In addition, the innovative SR3 (Selective Regional Regeneration Radio Repeated Pulse) technology enables precise targeting of abnormal pigmentation and vascular structures without damaging surrounding healthy tissue. This promotes melanin regulation, vascular normalisation, and collagen remodelling for clearer, healthier skin.
Many individuals have a compromised basement membrance due to sun exposure and intrinsic ageing. Remodelling this very layer between the epidermis and dermis prevents the migration of pigment cells to the deeper dermal layer. The treatment targets the root causes of melasma by regulating hyperactive melanocytes (pigment cells), strengthening damaged basement membrane, removing abnormal blood vessels in the skin, and increasing collagen and young fibroblast production.
You may observe some lightening and a smoother skin texture after the first session. Full results are usually observed after 5 sessions, the treatment sessions are performed once every 3 weeks.
The treatment is virtually painless with numbing cream.
Immediately following the treatment, there may be some mild redness and swelling which typically resolves within an hour.
Most patients are able to resume activities immediately post-treatment.
Exosomes are tiny vesicles, or “bubbles,” released by various cells in the human body. They carry bioactive molecules such as growth factors, amino acids, lipids, and peptides. Acting as messengers, these nanoparticles transmit signals to unhealthy cells, triggering them to regenerate.
How Exosome Treatment Works
As we age, cell function deteriorates and natural exosome levels decline. Exosome treatment introduces fresh exosomes that deliver targeted signals, instructing skin cells to repair and renew themselves. Depending on the specific signals transmitted, this can lead to a significant increase in collagen and elastin production, reduced pigmentation, improved wound healing, and decreased inflammation. The result is visibly plumper, firmer, brighter, and smoother skin.
At s.k.MED, the exosomes we use are meticulously extracted from botanical stem cells and processed using patented technology. The final product is highly purified, containing 49.2 billion particles and more than 1,000 types of growth factors and regenerative proteins. Combined with premium activators, it delivers a holistic and highly effective skin rejuvenation experience.
The following six images depict the penetration of exosome nano particles into the skin over 24 hours.
Anti-inflammation
Potent antioxidant
Regeneration
Melanin modulation
The exosome treatment is performed alongside microneedling or laser therapy. These procedures create micro-channels in the skin which facilitate the penetration and absorption of the exosomes. In addition, exosomes work synergistically with the skin’s natural healing processes to maximise the benefits of the device-based treatments.
Exosome treatment addresses the following:
Most patients require 4 to 6 sessions performed at 3 to 4-weekly intervals.
The procedure is generally well tolerated apart from mild redness which typically resolves within an hour.
The treatment is virtually painless with numbing cream.
Exosome Treatment is usually combined with microneedling, microneedling radiofrequency, or MicroLaserPeel.
This treatment belongs to a class of bio-remodelling “injectable skincare” that targets skin laxity and signs of ageing. By bio-stimulating the skin to produce and replace collagen, elastin, and adipocyte stem cells lost through the natural ageing process, it firms and tightens the skin, boosts hydration, and improves skin texture.
The injectable material boasts one of the highest concentrations of hyaluronic acid (64mg/2ml) among various types of injectables. This is made possible with NAHYCO® Technology, where 32mg of high molecular weight HA and 32mg of low molecular weight HA are bound together through thermal cross-linking to form the Hybrid Cooperative Complex (HCC) Hyaluronic Acid. The result is a stable, long-lasting product that spreads smoothly under the skin without the need for chemical cross-linking agents. This helps minimise post-procedural inflammation, enhances spreadability, and offers a superior safety profile with fewer injection points and reduced downtime.

Administration of a full 2 ml syringe requires only 5 injection points on each side of the face or neck. This reduces discomfort and the risk of bruising or haematoma.

Side effects are minimal. You may notice small bumps at the injection sites, bruising may also occur. The benefits will not be immediately visible, full results are typically observed 4-8 weeks after the second syringe.
A typical treatment program is made up of two syringes, administered 4 weeks apart, a third syringe may be necessary for patients with more severe laxity. Maintenance sessions should be repeated every 6-9 months.
Bio-remodelling HA can be combined with HIFU or SkinTyte for maximal skin tightening and lifting.
Local Dynamic Micro-Massage (LDM) is a non-invasive treatment that addresses skin concerns in both the epidermis and dermis. It utilises dual-frequency ultrasound technology at high frequencies to deliver a powerful micro-massage effect to the skin’s tissue structures. This dynamic stimulation activates fibroblasts, rejuvenates the skin matrix and connective tissue, enhances collagen cross-linking, and promotes healing at a cellular level. LDM is effective for a wide range of dermatological conditions and aesthetic concerns, improving overall skin health without downtime.
1. Reduces “bad enzymes” Matrix Metalloproteinases (MMPS)
MMPs contribute to inflammation and the breakdown of collagen. They are also implicated in metabolic disorders of the connective tissue, which can lead to conditions such as acne, eczema, and dermatitis. By inhibiting MMPs, LDM helps restore the skin’s normal collagen metabolism and reduces inflammatory responses.
2. Activates HSPs (heat shock proteins)
HSPs play a vital role in skin immunity and resilience. They are produced in response to environmental stressors such as UV radiation and extreme temperatures, and support the skin’s ability to repair and protect itself under stress.
3. Increase GAGs (glycosaminoglycans)
GAGs enhance cell metabolism and boost hyaluronic acid content in the skin. By increasing tissue turgor, they improve skin texture, tone, and reinforce the skin barrier—resulting in a plumper, more hydrated appearance.

Skin Ageing and Laxity
Fine lines, wrinkles, prominent nasolabial folds and marionette lines, skin rejuvenation and firming, body firming and toning.

Treatment of Chronic Skin Conditions
Dryness, acne, rosacea, flushing.

Scar Regeneration & Wound Healing
Hypertrophic scars, stretch marks, bruises.
Most ultrasound systems use a single frequency, typically in the range of 1 to a maximum of 5 MHz, the therapeutic effect is thus far below the superficial skin layers. LDM uses a special frequency of 10 MHz other than 1 and 3MHz, which allows the energy to work effectively on the epidermis and dermis, where disease processes take place. In addition, the system switches and combines frequencies at timed intervals, ensuing better dynamic pressure distribution in the tissue over several skin layers.

After cleansing the skin, a layer of gel is applied to the treatment area. An ultrasound probe is then gently glided over the targeted region. The procedure is comfortable, with no pain or downtime.
The treatment ranges from 15 to 30 minutes, depending on the indication or condition.
While improvement may be observed after just one session, for optimal and full results, LDM should be performed once every week or fortnight for the first six weeks. Maintenance sessions are recommended once every month to two months.
Dermatological conditions such as eczema or psoriasis may need up to eight treatments and in more complex and severe cases, ten to sixteen sessions.
Although LDM is a great treatment on its own, results are augmented when combined with other medical facial services, energy-based devices or injectables. In fact, it helps shorten procedural downtime by reducing inflammation, and increasing cell regeneration and metabolism.
Yes, LDM is suitable and safe for all skin types and colour.
Revitalise your skin with our HA (Hyaluronic Acid) Skin Booster treatment, designed to deeply hydrate, rejuvenate, and restore a youthful glow. Ideal for individuals looking to improve skin texture, tone, and elasticity, this non-invasive procedure delivers a series of tiny injections of hyaluronic acid directly into the skin, boosting moisture levels and enhancing overall skin health.
Our HA Skin Booster treatment is perfect for those with dry, tired, or dull skin, providing long-lasting hydration and a refreshed, plump appearance. With minimal downtime and quick results, it’s an excellent choice for anyone seeking subtle yet noticeable improvements without the need for surgery.
Benefits of HA Skin Booster Treatment:
Deep Hydration: Restores moisture, combating dry skin.
Smoother, Plumper Skin: Enhances texture and overall skin appearance.
Improved Elasticity: Helps firm and tighten skin, reduce signs of ageing, and improve pore appearance.
Even Skin Tone: Balances tone for a more radiant complexion.
Boosts Collagen Production: Promotes skin health and resilience.
Subtle, Natural Results: Non-invasive with noticeable improvements over time.
After your HA Skin Booster treatment, you can expect immediate hydration and a natural, refreshed glow. The skin may appear plumper and smoother, with improved texture and elasticity over time. Results typically develop gradually, with full effects visible within a few days to weeks.
In terms of side effects, they are generally minimal. You may experience some mild redness, swelling, or slight bruising at the injection sites, which usually subsides within a few hours to a few days. It’s also normal to feel some tenderness or a slight raised area where the injections were made. These effects are temporary and should resolve quickly.
A typical treatment program is made up of three initial sessions, with a session administered once every 4 weeks. Thereafter, one session every 4-6 months for maintenance is recommended.